Search results for "Foot Ulcer"
showing 10 items of 16 documents
Estudio de factores asociados con amputación, en pacientes diabéticos con ulceración en pie
2001
Objetivo: Analizar factores asociados con amputación en pacientes diabéticos que presentan úlceras en sus pies, con el fin de identificar sujetos con alto riesgo para amputación. Método: Hemos estudiado 152 diabéticos que acudieron a la Unidad del pie diabético desde enero de 1996 hasta junio de 1998 con úlceraciones en sus pies. En 14 de ellos fue necesaria la amputación. Se excluyeron sujetos con gangrena. Resultados: Los factores asociados con amputación fueron: antecedentes personales de amputación previa (odds ratio 3,7; 1,01-13,7), retinopatía proliferativa, osteomielitis y, de forma independiente, la presencia de vasculopatía (7,1; 1,88-27,2) e infección grave (14,4; 2,92-71,2). Conc…
Improving referral of patients with diabetic foot ulcer to specialised diabetes foot care units.
2021
Adenosine receptor agonists for promotion of dermal wound healing
2008
Wound healing is a dynamic and complex process that involves a well-coordinated, highly regulated series of events including inflammation, tissue formation, revascularization and tissue remodeling. However, this orderly sequence is impaired in certain pathophysiological conditions such as diabetes mellitus, venous insufficiency, chronic glucocorticoid use, aging and malnutrition. Together with proper wound care, promotion of the healing process is the primary objective in the management of chronic poorly healing wounds. Recent studies have demonstrated that A(2A) adenosine receptor agonists promote wound healing in normal and diabetic animals and one such agonist, Sonedenoson, is currently …
Human Achilles tendon glycation and function in diabetes
2016
Diabetic patients have an increased risk of foot ulcers, and glycation of collagen may increase tissue stiffness. We hypothesized that the level of glycemic control (glycation) may affect Achilles tendon stiffness, which can influence gait pattern. We therefore investigated the relationship between collagen glycation, Achilles tendon stiffness parameters, and plantar pressure in poorly ( n = 22) and well ( n = 22) controlled diabetic patients, including healthy age-matched (45–70 yr) controls ( n = 11). There were no differences in any of the outcome parameters (collagen cross-linking or tendon stiffness) between patients with well-controlled and poorly controlled diabetes. The overall effe…
Factores de riesgo de presión máxima plantar elevada en pacientes con polineuropatía diabética
2013
La diabetes mellitus (DM) es un problema creciente de salud pública en todo el mundo. En España la mayoría de estudios muestran ratios de prevalencia entre el 10% y el 15%. Los estudios de prevalencia de polineuropatía diabética (PNPD) muestran resultados muy dispares que oscilan entre un 22,7% a un 54%. Un 70% de las amputaciones de miembros inferiores suceden en personas con DM y un 85% de todas las amputaciones están precedidas por una úlcera. Se considera que el 25% de los pacientes con DM desarrollará úlcera plantar y un 2% requerirá amputación. Las complicaciones del pie diabético son de las más graves y costosas de la DM, siendo la amputación el paradigma de esta gravedad, y la úlcer…
OZONE IN THE TREATMENT OF MUSCULOSKELETAL INFECTIONS
2018
Ozone, an antibacterial, has a spectrum of action which is bigger than any antibiotic known today. Very few bacteria can resist the onslaught of ozone and this is again dependent on the route of delivery of the ozone- oxygen mixture. Musculoskeletal infections, mainly chronic osteomyelitis and foot ulcers, were taken as criteria for study. Chronic osteomyelitis of the long bones, mainly the tibia was preferred as route of entry into the marrow cavity is easier. Foot ulcers, diabetic or trophic were selected on random basis. Graphic representation based on dimension and pictures taken on regular intervals were the criteria for evidence of healing. All cases were subjected to a short course o…
Ácido hialurónico como tratamiento en úlcera neuropática: a propósito de un caso
2016
The prevalence of diabetic polyneuropathy in Spain is 22% increasing with age, standing at less than 5% in patients between 15 and 19 years and reaching 29.8% in those aged 70 to 74 years age. Infection is an important complication in Diabetic Foot, frequently associated with minor amputation and even lower extremity amputation. The study presents a clinical case of a 68-year-old man who consulted for a diabetic foot ulcer in the metatarseal area of the right foot, diagnosed two years ago and without healing success. An exploration protocol of the diabetic food was made. Afterwards, a surgical debridement was done and a cure procedure with pure hyaluronic acid, a bandage and foot unloading …
Impact of the COVID‐19 Epidemic on hospitalization for diabetic foot ulcers during lockdown: A French nationwide population‐based study
2021
AIMS/HYPOTHESIS: The aim of this study was to examine the impact of the COVID-19 epidemic on the hospitalization rates for diabetic foot ulcer (DFU), osteomyelitis and lower limb revascularization procedure in people with DFU. METHODS: This nationwide retrospective cohort study included hospital data on all people hospitalized in France for diabetes in weeks 2-43 in 2020, including the COVID-19 lockdown period, compared to same period in 2019. RESULTS: The number of hospitalizations for DFU decreased significantly in weeks 12-19 (during the lockdown) (p < 10-4 ). Hospitalization for foot osteomyelitis also decreased significantly in weeks 12-19 (p < 10-4 ). The trend was the same for lower …
The efficacy of sucrose-octasulphate dressing in neuro-ischaemic DFU considering factors influencing wound closure rate: a post-hoc analysis of the E…
2018
IF 6.023; International audience
Arterial stiffness, endothelial and cognitive function in subjects with type 2 diabetes in accordance with absence or presence of diabetic foot syndr…
2017
BACKGROUND: Endothelial dysfunction is an early marker of cardiovascular disease so endothelial and arterial stiffness indexes are good indicators of vascular health. We aimed to assess whether the presence of diabetic foot is associated with arterial stiffness and endothelial function impairment. METHODS: We studied 50 subjects with type 2 diabetes mellitus and diabetic foot syndrome (DFS) compared to 50 diabetic subjects without diabetic foot, and 53 patients without diabetes mellitus, by means of the mini mental state examination (MMSE) administered to evaluate cognitive performance. Carotid-femoral pulse wave velocity (PWV) and augmentation index (Aix) were also evaluated by Applanation…